Vastus Lateralis Muscle Anatomy

OriginGreater trochanter
Intertrochanteric line
Lateral aspect of the linea aspera
Gluteal tuberosity
Lateral intermuscular septum
InsertionLateral aspect of the patella
The quadriceps tendon, which inserts into the patellar tendon, which connects onto the tibial tuberosity
ActionKnee extension
NerveFemoral nerve (L2, L3, L4)
ArteryFemoral artery

Location & Overview

The vastus lateralis is a large, thick muscle located in the anterior compartment of the thigh. It is one of the four quadricep muscles, which together make up the quadriceps femoris muscle group, responsible for extending the knee and stabilising the knee joint [1] [2]. The vastus lateralis is the most lateral and largest of these quadricep muscles, playing an important role in maintaining balance and stability during physical activities [3] The other three quadricep muscles are the vastus intermedius, vastus medialis, and rectus femoris [4] [5]. Some studies have also reported a fusion of the vastus lateralis and vastus intermedius muscles [6] [7]. In extreme cases of this fusion, the two muscle present as an almost complete fusion [8].

The vastus lateralis is not only essential for the proper functioning of the lower limb but also serves as a common site for intramuscular injections due to its large size and accessibility [9] [10].

Common pathologies involving the vastus lateralis muscle include muscle strain, tendinopathy, and muscle imbalances, which may contribute to conditions such as patellofemoral pain syndrome and iliotibial band syndrome [11] [12]. Strengthening exercises targeting the vastus lateralis can help prevent injuries and improve overall lower limb function. Research has shown that exercises such as squats, lunges, leg presses, and step-ups effectively activate the vastus lateralis and other quadriceps muscles [13] [14].

Image of the vastus lateralis muscle from a superficial view

Here we can see the vastus lateralis muscle from a superficial view.

Image of the vastus lateralis muscle

Here we can see the vastus lateralis muscle in isolation.

Origin & Insertion

The vastus lateralis originates from multiple locations on the femur. These locations include the greater trochanter, which is a prominent bony protrusion close to the hip joint; the intertrochanteric line, a ridge that connects the greater and lesser trochanters; the lateral aspect of the linea aspera, a vertical ridge on the posterior surface of the femur; the gluteal tuberosity, a roughened area on the proximal end of the femur; and the lateral intermuscular septum [15] [16]. The lateral intermuscular septum of the thigh is a fold of deep fascia that separates the anterior compartment of the thigh from the posterior compartment. It divides the vastus lateralis and the biceps femoris muscle, providing an origin point for the vastus lateralis [17] [18].

The vastus lateralis inserts into the quadriceps tendon, which attaches to the patellar tendon. The patellar tendon inserts onto the tibial tuberosity, a bony prominence located on the front of the tibia below the knee joint. Additionally, the vastus lateralis also inserts onto the lateral aspect of the patella, the triangular-shaped bone that forms the kneecap [19] [20].

Image of the anterior origins of the vastus lateralis highlighted in red

Here we can see the anterior origins of the vastus lateralis, highlighted in red, on the anterior side of the femur (greater trochanter and intertrochanteric line).

Image of the posterior origins of the vastus lateralis highlighted in red

Here we can see the posterior origins of the vastus lateralis, highlighted in red, on the posterior side of the femur (lateral aspect of the linea aspera, gluteal tuberosity, and lateral intermuscular septum).

Image of the patella insertion of the vastus lateralis

Here we can see an insertion of the vastus lateralis, highlighted in blue, on lateral side of the patellar.

Image of the patellar tendon insertion

Here we can see the insertion of the patellar tendon at the tibial tuberosity. The vastus lateralis inserts into the quadriceps tendon which then inserts into the patellar tendon.


The vastus lateralis muscle’s primary action is knee extension, working alongside the other muscles of the quadriceps femoris group to extend the knee during activities such as walking, running, and jumping [21]. It also plays an important role in stabilising the knee joint, working together with the vastus medialis to maintain proper tracking of the patella and prevent excessive lateral movement [22]. The vastus lateralis also plays a role in eccentric control during deceleration, helping to absorb impact forces when landing from a jump or slowing down from a sprint [23].

Image of a person demonstrating the movement of knee extension.

In this image, you can see an example of knee extension, which is the action of straightening out your leg at the knee joint. The opposite movement of knee flexion is knee extension. The vastus lateralis’ main function is knee extension.


The vastus lateralis muscle is innervated by the femoral nerve, which arises from the lumbar plexus, a network of nerves formed by the anterior rami of spinal nerve roots L2, L3, and L4 [24] [25]. The femoral nerve descends through the psoas major muscle in the abdomen and enters the thigh by passing beneath the inguinal ligament, a fibrous band that runs from the anterior superior iliac spine to the pubic tubercle, forming the base of the abdominal wall [26].

Blood Supply

The vastus lateralis primarily gets its blood supply from the lateral circumflex femoral artery. It also receives some blood from the perforating arteries of the profunda femoris [27].

Want some flashcards to help you remember this information? Then click the link below:
Vastus Lateralis Flashcards

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