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Location & Overview
The semitendinosus muscle is one of the three muscles that make up the hamstring muscle group. The other two hamstring muscles are the semimembranosus and biceps femoris muscles. The semitendinosus is the most centrally located hamstring muscle. It is located in the posterior compartment of the thigh, between the biceps femoris and semimembranosus. The semitendinosus muscle is more superficial than the semimembranosus (meaning it is located closer to the skin’s surface) and covers a large portion of the semimembranosus. The attachments of the semitendinosus are relatively close to those of the semimembranosus, which shows their close anatomical relationship.[1]








Origin & Insertion
The semitendinosus originates at the superior portion of the ischial tuberosity. The ischial tuberosity is a bony protrusion located on the posterior aspect of the ischium, which is the lower part of the hip bone. This origin point is shared with the other two hamstring muscles (semimembranosus and biceps femoris).[2,1]
The muscle then travels down the posterior and medial portion of the thigh, where it inserts below the knee joint on the medial surface of the superior part of the tibia. This insertion is part of the group of tendons known as the ‘pes anserinus,’ which includes the tendons of the semitendinosus, sartorius, and gracilis muscles.[2,1]


Action & Function
The semitendinosus muscle plays a role in several movements at the hip and knee joints. Its primary functions include flexing the knee joint, extending the hip joint, and medially rotating the tibia on the femur when the knee is flexed.[2,3]
Flexion of the knee joint involves bending the knee, which brings the lower leg closer to the back of the thigh. Extension of the hip joint involves moving the thigh backward relative to the hip, such as when pushing off the ground when walking.[2,3]
Furthermore, the semitendinosus muscle assists in medially (internally) rotating the tibia on the femur when the knee is flexed. This action involves turning the lower leg (tibia) inward relative to the thigh without moving the thigh itself.[2,3]



Innervation
The semitendinosus muscle receives its innervation from the tibial division of the sciatic nerve, which arises from nerve roots L5, S1, and S2.[3] The sciatic nerve is the largest nerve in the body and provides motor and sensory functions to the lower limbs.[4]
The tibial division of the sciatic nerve supplies the motor signals necessary for the semitendinosus muscle to perform its actions, such as flexing the knee, extending the hip, and medially rotating the tibia on the femur when the knee is flexed.[3] In addition, the sciatic nerve also carries sensory information from the skin and deeper structures of the lower limb, enabling the perception of touch, pain, and temperature.[4]


Blood Supply
The blood supply to the semitendinosus muscle is provided primarily by the inferior gluteal artery and the perforating arteries. The inferior gluteal artery is a branch of the internal iliac artery, which supplies blood to the gluteal region and the posterior thigh muscles, including the hamstring muscles. The perforating arteries are branches of the deep femoral artery (profunda femoris) and perforate the adductor magnus muscle to supply blood to the posterior compartment of the thigh.[5]
References
- [1] Moore KL, Agur AMR, Dalley AF. Clinically Oriented Anatomy. 8th ed. Philadelphia: Lippincott Williams & Wilkins; 2017.
- [2] Rodgers CD, Raja A. Anatomy, Bony Pelvis and Lower Limb, Hamstring Muscle. (Updated 2021 Aug 11). In: StatPearls (Internet). Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK546688/
- [3] Afonso J, Rocha-Rodrigues S, Clemente FM, et al. The Hamstrings: Anatomic and Physiologic Variations and Their Potential Relationships With Injury Risk. Front Physiol. 2021;12:694604. Published 2021 Jul 7. doi:10.3389/fphys.2021.694604
- [4] Standring S. (2015). Gray’s Anatomy: The Anatomical Basis of Clinical Practice, 41st Edn. Amsterdam: Elsevier.
- [5] Tomaszewski KA, Henry BM, Vikse J, Pękala P, Roy J, Svensen M, Guay D, Hsieh WC, Loukas M, Walocha JA. Variations in the origin of the deep femoral artery: A meta-analysis. Clin Anat. 2017 Jan;30(1):106-113. doi: 10.1002/ca.22691. Epub 2016 Feb 2. PMID: 26780216.
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